The patient presented with a nonspecified lesion of the oral cavity that had grown continuously over the past 2 years. Ppt cutaneous tuberculosis powerpoint presentation free. Cutaneous tuberculosis cutaneous tuberculosis has various clinical and morphological forms depending on the mode of entry and whether it is primary or secondary infection. Longlasting cutaneous tuberculosis owing to mycobacterium. Cutaneous tuberculosis tb is essentially an invasion of the skin by mycobacterium tuberculosis, the same bacteria that cause tb of the lungs pulmonary tb. The skin weighs an average of four kilograms, covers an area of two square meters, and is made of three distinct layers. It still meets all the criteria for prioritization of a public health disorder, i. Ppt cutaneous tuberculosis powerpoint presentation. Immunology primary complexghon focus, lymphangitis. Nontuberculous mycobacteria can also cause nonpulmonary infection, including lymphadenitis and cutaneous disease.
Tuberculosis tuberculosis b lint beatrix md, phd szte, dpt. Cutaneous tuberculosis article about cutaneous tuberculosis. A high index of suspicion is required and unusual skin lesions presenting in these. Tuberculosis airborne disease caused by the bacterium mycobacterium tuberculosis m. The main causal agent is mycobacterium tuberculosis but mycobacterium bovis may be involved. Cutaneous forms of tuberculosis are a rare clinical manifestation of m.
If you have any concerns with your skin or its treatment, see a dermatologist for. Cutaneous tuberculosis ctb is uncommon, comprising 11. This is especially true in immunocompromised patients, where even mycobacteria not previously thought to cause disease may do so. Cutaneous tuberculosis overview and current treatment. Cutaneous tuberculosis is the property of its rightful owner.
There have been various methods of classifying infection. The lesions may ultimately develop into disfiguring skin ulcers if left untreated. Due to persistent lockjaw, food intake now was nearly impossible. In areas such as india or china where tb prevalence is high, cutaneous manifestations of tb overt infection or tuberculids are found in less than 0. It is the most common mycobacterium tuberculosis skin infection. Cutaneous tuberculosis, although rare, can cause significant diagnostic confusion to physicians, surgeons and dermatologists alike. Cutaneous tuberculosis, cutaneous atypical mycobacterial infection, lymphoma, invasive fungal infections. Globally, it is the leading cause of deaths resulting from a single infectious disease.
Cutaneous tuberculosis occurs rarely, despite a high and increasing prevalence of tuberculosis worldwide. Introduction mycobacterium tuberculosis term mycobacterium. Cutaneous tuberculosis tuberculosis cutaneous conditions. A variety of t and bcell neoplasms can involve skin, either primarily or secondarily. The microscopic manifestations have been categorized into five groups. Lupus vulgaris is a progressive form of cutaneous tuberculosis which is acquired either exogenously by direct inoculation of the bacilli into the skin or endogenously by hematogenous or lymphatic spread from an underlying infected focus in a sensitized host with a moderate to high degree of immunity to mycobacterium tuberculosis 1. The most common site of involvement is the ileocaecal region, other locations of involvement, in order of descending frequency, are the ascending colon, jejunum, appendix, duodenum, stomach. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Primary inoculation tuberculosis of the skin is the cutaneous analogue of the pulmonary ghon focus primary cutaneous tuberculosis may be associated with tattooing, ritual circumcision, nose piercing, inoculation of homeopathic solutions or injury by contaminated objects to laboratory workers, surgeons or prosectors. In primary infection, there is no previous sensitisation and tuberculous chancre, acute miliary disseminated tuberculosis. Lupus vulgaris also known as tuberculosis luposa are painful cutaneous tuberculosis skin lesions with nodular appearance, most often on the face around the nose, eyelids, lips, cheeks, ears and neck.
A classification of cutaneous tuberculosis is shown in table 1. Tuberculosis tb is still prevalent in many developing countries and can pose a new potential threat to global health due to international migration. Traditionally infection has been divided into primary infection, where there has been no previous exposure to the organism, and secondary tuberculosis, resulting from reinfection histology of cutaneous tuberculosis. Incidence of tuberculosis pulmonary 90% extrapulmonary 10% cutaneous 11. Winner of the standing ovation award for best powerpoint templates from presentations magazine. View genitourinary tuberculosis ppts online, safely and virusfree. Cutaneous tuberculosis can be acquired exogenously or endogenously and present as a multitude of differing clinical morphologies.
It is a rare presentation of cutaneous tuberculosis predominantly in severely immunocompromised host, demonstrating anergy. This type occurs if a cutaneous lesion on the face spreads to involve the nose or mouth. Author summary cutaneous leishmaniasis displays a wide spectrum of clinical and microscopic findings. Cutaneous tuberculosis rob roy macgregor, md uberculosis tb has been part of the human experience since prehistoric times. Many conditions affect the human integumentary systemthe organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. Classification beyt inoculation tuberculosis exogenous.
Unusual host inflammatory responses may be elicited by certain pathogens, including reactions with an inherent capacity for misdiagnosis as neoplasia. According to the infection route, cutaneous tuberculosis can be acquired by exogenous or endogenous. Ppt pulmonary tuberculosis powerpoint presentation. Symptoms vary by site but generally include fever, malaise, and weight loss. A high index of suspicion is required and unusual skin lesions presenting in these circumstances. The most common form of the disease is tuberculosis of the lungs pulmonary consumption, or phthisis, but the intestines, bones and joints, the skin, and the genitourinary, lymphatic, and nervous systems may also be affected.
Immunology primary complexghon focus, lymphangitis, lymphadenitis tuberculin. A 55yearold homeless man with cachexia and sepsis presented to our outpatient clinic in magdeburg, germany. A clinicoepidemiological study of cutaneous tuberculosis in a tertiary care teaching hospital in andhra pradesh, india background. When someone comes into contact with tuberculosis or feels as if they become infected by tuberculosis, they should call a doctor and order a skin test. Cutaneous tuberculosis 1 cutaneous tuberculosis 2 mycobacterium. Clinical subtypes of cutaneous tuberculosis a classification of cutaneous tuberculosis is shown in table 1. A free powerpoint ppt presentation displayed as a flash slide show on id. Cutaneous tuberculosis occurs rarely, despite a high and increasing. The high prevalence of tb worldwide, its transmissible nature, and the significant morbidity and mortality associated with this infection account for the status of tb as a major public health concern. This medical powerpoint template will fit presentations on medical tests, tuberculosis disease, distribution of tuberculosis, tuberculin tests, pulmonary tb, tubercle bacillus, etc. The spectrum of infectious diseases with potential skin involvement, either primary or secondary to systemic disease, is vast. Cutaneous tuberculosis ctb is an uncommon small subset of extrapulmonary tuberculosis, comprising 11.
Tuberculosis tb can affect any part of the body, and nonpulmonary tb accounted for 43% of notifications in england and wales in 2007. Cutaneous tuberculosis free download as powerpoint presentation. Cutaneous and pulmonary botryomycosis the lancet infectious. Tuberculosis outside the lung usually results from hematogenous dissemination.
Tuberculosis tb continues to draw special attention from health care professionals and society as a whole. Mycobacterium tuberculosis and certain atypical mycobacteria may cause a spectrum of cutaneous disease and may sometimes pose difficult diagnostic problems table 1. This is an example of tuberculosis of the skin it is normally referred to as warty t. Tuberculosis tb is a mycobacterial infection that most frequently occurs due to infection with mycobacterium tuberculosis, an acidfast bacillus. Ppt cutaneous tuberculosis powerpoint presentation free to download id. Diagnosis is most often by sputum smear and culture and, increasingly, by rapid molecularbased diagnostic tests. After surgical excision of the aneurysm and revascularization using femoral vein, cutaneous manifestations of m tuberculosis infection in the foot complicated the course. Nonpulmonary tuberculosis and mycobacterial infection. It is a rare presentation of cutaneous tuberculosis predominantly in severely immuno. The major function of this system is as a barrier against the external environment.
A more accurate classification of ctb includes inoculation tuberculosis, tuberculosis from an endogenous source and haematogenous tuberculosis. Traditionally infection has been divided into primary infection, where there has been no previous exposure to the organism, and secondary tuberculosis, resulting from reinfection. Cutaneous tuberculosis is caused by infection by mycobacterium tuberculosis. With the improvement of hygiene habits in the general population, the improvement of living standards, the use of the bcg vaccine, and the introduction of effective chemotherapy, there was a significant decrease in the number of cases. A clinicoepidemiological study of cutaneous tuberculosis in a. During the previous 6 months the skin of his face and left shoulder had developed erosions and had. Disseminated blastomycosis with cutaneous lesions mimicking. The cutaneous manifestations of mycobacterial diseases. As an uncommon form of extrapulmonary tb, cutaneous tb is complicated in its clinical manifestation, pathogenesis, and classification. Cutaneous tuberculosis an increasingly rare entity in.
Cutaneous tuberculosis although 1 of 3 individuals on this planet is infected with tubercle bacillus, the incidence of cutaneous tb appears low. Tuberculosis is defined as an infectious disease caused by a bacterium. Victor et al first described use of pcr in cutaneous tb confirmation of m. Sometimes infection directly extends from an adjacent organ. Cutaneous tuberculosis continues to be one of the most elusive and more difficult diagnoses to make for dermatologists practicing in developing countries. Cutaneous tb is a relatively uncommon form of extrapulmonary tb tb infection of other organs and tissues.
The type of granulomatous response defined in group v is usually tuberculoid in nature with exceedingly rare cases described with necrotizing granulomas in contrast to cutaneous infections with tuberculosis and other. Current, emerging, reemerging andor recently recognized pathogens or infections of major significance include. The present study was done to document the most common type of cutaneous tuberculosis, atypical presentations if any and response to directly observed therapy short course dots. A clinicoepidemiological study of cutaneous tuberculosis. Although 1 of 3 individuals on this planet is infected with tubercle bacillus, the incidence of cutaneous tb appears low. Disseminated blastomycosis with cutaneous lesions mimicking tuberculosis previous article advancing the public health applications of chlamydia trachomatis serology a 37yearold man living in northwest ohio, usa, presented with a cough, haemoptysis, and weight loss, all observed for 2 months.
Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Classic bone lesions have been shown in stone age human skeletons, and recent use of polymer ase chain reaction probes have demonstrated the mycobacterium tuberculosis genome in mummified remains from ancient times. Not only because they have to consider a wider differential diagnosis leishmaniasis, leprosy, actinomycosis, deep fungal infections, etc but also because of the difficulty in obtaining a microbiological confirmation. We present a case of cutaneous tuberculosis caused by m bovis, considered to be sarcoidosis for14 years until discovered by immunosuppressive therapy. What is cutaneous tuberculosis cutaneous tuberculosis tb is essentially an invasion of the skin by mycobacterium tuberculosis, the same bacteria that cause tb of the lungs pulmonary tb.
Cutaneous tuberculosis final ppt linkedin slideshare. It can also be a crippling and deadly disease, and is on the rise in both developed and developing worlds. Cutaneous tb can be divided into two major categories, true cutaneous tb and tuberculid, depending on the. Jul 16, 2014 rd worlds population infected with mycobacterium tuberculosis bacteria in india cutaneous manifestations of tb including tuberculids are found in jul 21, 20 introduction. Cutaneous tuberculosis definition of cutaneous tuberculosis. Extrapulmonary tuberculosis tb infectious diseases msd. Update on cutaneous tuberculosis pubmed central pmc. Mark the false alternative regarding cutaneous tuberculosis laboratory diagnosis.
Cutaneous tuberculosis 2007 clinics in dermatology. Neurothekeoma bizarre cutaneous neurofibroma, cutaneous lobular neuromyxoma, myxoma of the nerve sheath, myxomatous perineurioma, nerve sheath myxoma nevus flammeus capillary malformation, portwine stain nevus flammeus nuchae stork bite nevus lipomatosus superficialis nevus lipomatosis of hoffman and zurhelle nevus oligemicus. An update on cutaneous infections diagnostic histopathology. Cutaneous mycobacterial infections are difficult to diagnose in paucibacillary forms such as lupus vulgaris. Even in countries such as india and china where tb still commonly occurs, cutaneous outbreaks. Diagnosis of nonpulmonary mycobacterial infection requires highquality clinical specimens and relies on microscopy, culture, and.